Etudes, Recherche

Etudes en cours dans la Policlinique d’allergologie et d’immunologie

• «Biomarkers for allergen-specific immunotherapy and immune tolerance» en collaboration avec le SIAF (Davos)
• Optimierung der Medikamentenallergie-Diagnostik: Bestimmung von Granulysin und Granzym B in Medikamenten-stimulierten Zellkulturen im Vergleich zum LTT (ADR-AC)
• Nahrungsmittelallergie (Erdnuss) bei Spenderorganen
• Does a deeper phenotypic, genetic and functional characterization of B and T cells lead to a better classification and standardized diagnosis in CVID patients?
• Sind Basophile von Allergiker resistenter als Zellen gesunder Probanden gegenüber Apoptose-induzierenden Liganden und Mediatoren (z.B. TRAIL, IFN-a)?
• Drug hypersensitivity cohort. A prospective cohort study to investigate the correlation between clinical/histopathological criteria and the rate of sensitisation in skin tests in drug allergy
• Mechanisms in drug hypersensitivity: humoral and cellular immune response to drugs
• Hypersensitivity reactions to drugs – how do the T celll recognition pattern and the HLA restriction influence the clinical picture?
• Investigation of the transient nature of chronic spontaneous urticaria
• Investigation of the involvement of specific T cells in the pathogenesis of non-chemotherapy drug-induced agranulocytosis.
• Retrospektive Evaluation von Klinik, Hauttest und In Vitro Verfahren bei Medikamentenallergien
• Clinical phenotype, cytokine pattern and T-cell phenotype in patients with drug reaction with eosinophilia and systemic symptoms
• Chlorhexidinallergie – Kreuzreaktivität
• Establishment of a cell-basedfunctional assay for the diagnosis of allergies